KEGG   Bos taurus (cow): 281972
Entry
281972            CDS       T01008                                 
Symbol
PDE5A
Name
(RefSeq) cGMP-specific 3',5'-cyclic phosphodiesterase
  KO
K13762  cGMP-specific 3',5'-cyclic phosphodiesterase [EC:3.1.4.35]
Organism
bta  Bos taurus (cow)
Pathway
bta00230  Purine metabolism
bta01100  Metabolic pathways
bta04022  cGMP-PKG signaling pathway
Brite
KEGG Orthology (KO) [BR:bta00001]
 09100 Metabolism
  09104 Nucleotide metabolism
   00230 Purine metabolism
    281972 (PDE5A)
 09130 Environmental Information Processing
  09132 Signal transduction
   04022 cGMP-PKG signaling pathway
    281972 (PDE5A)
Enzymes [BR:bta01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.4  Phosphoric-diester hydrolases
    3.1.4.35  3',5'-cyclic-GMP phosphodiesterase
     281972 (PDE5A)
SSDB
Motif
Pfam: PDEase_I GAF GAF_2
Other DBs
NCBI-GeneID: 281972
NCBI-ProteinID: NP_776842
BGD-bta: BT10779
Ensembl: ENSBTAG00000024888
VGNC: 32678
UniProt: Q28156
Structure
Position
6:5745681..5894235
AA seq 865 aa
MERAGPGSARPQQQWDQDSVEAWLDDHWDFTFSYFVRKGTREMVNAWFAERVHTIPVCKE
GIKGHTESCSCPLQPSPRAESSVPGTPTRKISASEFDRPLRPIVIKDSEGTVSFLSDSDK
KEQMPLTSPRFDNDEGDQCSRLLELVKDISSHLDVTALCHKIFLHIHGLISADRYSLFLV
CEDSSNDKFLISRLFDVAEGSTLEEASNNCIRLEWNKGIVGHVAAFGEPLNIKDAYEDPR
FNAEVDQITGYKTQSILCMPIKNHREEVVGVAQAINKKSGNGGTFTEKDEKDFAAYLAFC
GIVLHNAQLYETSLLENKRNQVLLDLASLIFEEQQSLEVILKKIAATIISFMQVQKCTIF
IVDEDCSDSFSSVFHMECEELEKSSDTLTRERDANRINYMYAQYVKNTMEPLNIPDVSKD
KRFPWTNENMGNINQQCIRSLLCTPIKNGKKNKVIGVCQLVNKMEETTGKVKAFNRNDEQ
FLEAFVIFCGLGIQNTQMYEAVERAMAKQMVTLEVLSYHASAAEEETRELQSLAAAVVPS
AQTLKITDFSFSDFELSDLETALCTIRMFTDLNLVQNFQMKHEVLCKWILSVKKNYRKNV
AYHNWRHAFNTAQCMFAALKAGKIQKRLTDLEILALLIAALSHDLDHRGVNNSYIQRSEH
PLAQLYCHSIMEHHHFDQCLMILNSPGNQILSGLSIEEYKTTLKIIKQAILATDLALYIK
RRGEFFELIMKNQFNLEDPHQKELFLAMLMTACDLSAITKPWPIQQRIAELVATEFFDQG
DRERKELNIEPADLMNREKKNKIPSMQVGFIDAICLQLYEALTHVSEDCFPLLDGCRKNR
QKWQALAEQQEKTLINGESSQTKRN
NT seq 2598 nt   +upstreamnt  +downstreamnt
atggagagggccggccccggctccgcgcggccgcaacagcaatgggaccaggactcggtc
gaagcgtggctggacgatcactgggactttaccttctcttactttgttaggaaaggcacc
agagaaatggtcaacgcatggtttgctgagagagttcacaccattcctgtgtgcaaggaa
ggaatcaagggccacacggaatcctgctcttgccccttgcagccaagtccccgtgcagag
agcagtgtccctggaacaccaaccaggaagatctctgcctctgaattcgatcggccgctt
agacccatcgttatcaaggattctgagggaactgtgagcttcctctctgactcagacaag
aaggaacagatgcctctaacctccccacggtttgataatgatgaaggggaccagtgctcg
agactcttggaattagtgaaagatatttctagtcacttggatgtcacagccttatgtcac
aaaattttcttgcacatccatggactcatctccgccgaccgctactccttattcctcgtc
tgtgaggacagctccaacgacaagtttcttatcagccgcctctttgatgttgcagaaggt
tcaacactggaagaagcttcaaacaactgcatccgcttagagtggaacaaaggcatcgtg
ggacacgtggccgcttttggcgagcccttgaacatcaaagacgcctatgaggatcctcga
ttcaatgcagaagttgaccaaattacaggctacaagacacaaagtattctttgtatgcca
attaagaatcatagggaagaggttgttggtgtagcccaggccatcaacaagaaatcagga
aatggtgggacattcactgaaaaagacgaaaaggactttgctgcttacttggcattttgt
ggaattgttcttcataatgctcaactctatgagacttcactgctggagaacaagagaaat
caggtgctgcttgaccttgctagcttaatttttgaagaacaacaatcattagaagtaatt
ctaaagaaaatagctgccactattatctctttcatgcaggtgcagaaatgcaccattttc
atagtggatgaagattgctccgattctttttctagtgtgtttcacatggagtgtgaggaa
ttagaaaaatcgtcagatactttaacacgggaacgtgatgcaaacagaatcaattacatg
tatgctcagtatgtcaaaaataccatggaaccacttaatatcccagacgtcagtaaggac
aaaagatttccctggacaaatgaaaacatgggaaatataaaccagcagtgcattagaagt
ttgctttgtacacctataaaaaatggaaagaagaacaaagtgataggggtttgccaactt
gttaataagatggaggaaaccactggcaaagttaaggctttcaaccgcaacgatgaacag
tttctggaagctttcgtcatcttttgtggcttggggatccagaacacacagatgtacgaa
gcagtggagagagccatggccaagcaaatggtcacgttagaggttctgtcttatcatgct
tcagctgcagaggaagaaaccagagagctgcagtccttagcggctgctgtggtaccatct
gcccagacccttaaaatcactgacttcagcttcagcgactttgagctgtctgacctggaa
acagcactgtgcacaatccggatgttcactgacctcaaccttgtgcagaacttccagatg
aaacatgaggtcctttgcaagtggattttaagtgtgaagaagaactatcggaagaacgtc
gcctatcataattggagacatgcctttaatacagctcagtgcatgtttgcggcactaaaa
gcaggcaaaattcagaagaggctgacggacctggagatacttgcactgctgattgctgcc
ttaagccatgatctggatcaccgtggtgtcaataactcatacatacagcgaagtgaacac
ccacttgctcagctctactgccattcaatcatggagcatcatcattttgatcagtgcctg
atgatccttaatagtcctggcaatcagattctcagtggcctctccattgaagagtataag
accaccctgaagatcatcaagcaagctattttagccacagacctagcactgtacataaag
agacgaggagaattttttgaacttataatgaaaaatcaattcaatttggaagatcctcat
caaaaggagttgtttttagcgatgctgatgacagcttgtgatctttctgcaattacaaaa
ccctggcctattcaacaacggatagcagaacttgttgccactgaattttttgaccaagga
gatagagagaggaaagaactcaacatagagcccgctgatctaatgaaccgggagaagaaa
aacaaaatcccaagtatgcaagttggattcatagatgccatctgcttgcaactgtatgag
gccttgacccatgtgtcggaggactgtttccctttgctggacggctgcagaaagaacagg
cagaaatggcaggctcttgcagaacagcaggagaagacactgatcaatggtgaaagcagc
cagaccaagcggaactga

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Ontology (2)   
   KEGG BRITE (2)   
Pathway (3)   
   KEGG PATHWAY (3)   
Chemical substance (3)   
   KEGG COMPOUND (3)   
Chemical reaction (2)   
   KEGG ENZYME (1)   
   KEGG REACTION (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (8)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   BGD-BTA (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (5)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (3)   
DNA sequence (5)   
   RefSeq(nuc) (3)   
   GenBank (1)   
   EMBL (1)   
3D Structure (2)   
   PDB (2)   
Protein domain (3)   
   Pfam (3)   
All databases (41)   

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